Teaching Platform Anatomy --- University of Fribourg  Department of Oncology, Microbiology and Immunology  

Selected publications by Luis Filgueira

Full list on Google Scholar

2018

Evaluation of Extracellular Vesicle Function During Malaria Infection. Andrea Hernández-Castañeda M, Mbagwu S, Babatunde KA, Walch M, Filgueira L, Mantel PY. J Vis Exp. 2018 Feb 14;(132). doi: 10.3791/57067

Malaria infected red blood cells release small regulatory RNAs through extracellular vesicles. Babatunde KA, Mbagwu S, Hernández-Castañeda MA, Adapa SR, Walch M, Filgueira L, Falquet L, Jiang RHY, Ghiran I, Mantel PY. Sci Rep. 2018 Jan 17;8(1):884. doi: 10.1038/s41598-018-19149-9

The posterior ridge of the greater tuberosity of the humerus: a suitable landmark for the posterior approach to the shoulder joint? Grob K, Monahan RH, Manestar M, Filgueira L, Zdravkovic V. J Shoulder Elbow Surg. 2018 Apr;27(4):635-640. doi: 10.1016/j.jse.2017.10.034

Silver-nanoparticles increase bactericidal activity and radical oxygen responses against bacterial pathogens in human osteoclasts. Aurore V, Caldana F, Blanchard M, Kharoubi Hess S, Lannes N, Mantel PY, Filgueira L, Walch M. Nanomedicine. 2018 Feb;14(2):601-607. doi: 10.1016/j.nano.2017.11.006 

2017

Microglia at center stage: a comprehensive review about the versatile and unique residential macrophages of the central nervous system. Lannes N, Eppler E, Etemad S, Yotovski P, Filgueira L. Oncotarget. 2017 Dec 11;8(69):114393-114413. doi: 10.18632/oncotarget.23106

Production and Characterization of Extracellular Vesicles in Malaria. Mbagwu S, Walch M, Filgueira L, Mantel PY. Methods Mol Biol. 2017;1660:377-388. doi: 10.1007/978-1-4939-7253-1_31.

The interaction between the vastus medialis and vastus intermedius and its influence on the extensor apparatus of the knee joint. Grob K, Manestar M, Filgueira L, Kuster MS, Gilbey H, Ackland T. Knee Surg Sports Traumatol Arthrosc. 2017 Jan 25. doi: 10.1007/s00167-016-4396-3.

Interactions of human microglia cells with Japanese encephalitis virus. Lannes N, Neuhaus V, Scolari B, Kharoubi-Hess S, Walch M, Summerfield A, Filgueira L. Virol J. 2017 Jan 14;14(1):8. doi: 10.1186/s12985-016-0675-3. PMID:28088249

Regulation of inflammation in Japanese encephalitis. Lannes N, Summerfield A, Filgueira L. J Neuroinflammation. 2017 Aug 14;14(1):158. doi: 10.1186/s12974-017-0931-5.

Experience from an optional dissection course in a clinically-orientated concept to complement system-based anatomy in a reformed curriculum. Eppler E, Serowy S, Link K, Filgueira L. Anat Sci Educ. 2017 Jun 13. doi: 10.1002/ase.1707.

2016

The tensor of the vastus intermedius the fifth muscle of the extensor apparatus of the knee joint. Grob K, Ackland T, Kuster MS, Manestar M, Filgueira L. Clin Anat. 2016 Jan 6. doi: 10.1002/ca.22680.

2015

A High Yield and Cost-efficient Expression System of Human Granzymes in Mammalian Cells. Dotiwala F, Fellay I, Filgueira L, Martinvalet D, Lieberman J, Walch M. J Vis Exp. 2015 Jun 10;(100):e52911. doi: 10.3791/52911.

Potential Risk to the Superior Gluteal Nerve During the Anterior Approach to the Hip Joint: An Anatomical Study. Grob K, Manestar M, Ackland T, Filgueira L, Kuster MS. J Bone Joint Surg Am. 2015 Sep 2;97(17):1426-31. doi: 10.2106/JBJS.O.00146.

Distal extension of the direct anterior approach to the hip poses risk to neurovascular structures: an anatomical study. Grob K, Monahan R, Gilbey H, Yap F, Filgueira L, Kuster M. J Bone Joint Surg Am. 2015 Jan 21;97(2):126-32. doi: 10.2106/JBJS.N.00551

HDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with Neurofascins. Brügger V, Engler S, Pereira JA, Ruff S, Horn M, Welzl H, Münger E, Vaquié A, Sidiropoulos PN, Egger B, Yotovski P, Filgueira L, Somandin C, Lühmann TC, D'Antonio M, Yamaguchi T, Matthias P, Suter U, Jacob C. PLoS Biol. 2015 Sep 25;13(9):e1002258. doi: 10.1371/journal.pbio.1002258. eCollection 2015 Sep.

2013

Cisplatin induces differentiation of breast cancer cells. Prabhakaran P, Hassiotou F, Blancafort P, Filgueira L. Front Oncol. 2013 Jun 3;3:134. doi: 10.3389/fonc.2013.00134.

Expression of the Pluripotency Transcription Factor OCT4 in the Normal and Aberrant Mammary Gland. Hassiotou F, Hepworth AR, Beltran AS, Mathews MM, Stuebe AM, Hartmann PE, Filgueira L, Blancafort P. Front Oncol. 2013 Apr 11;3:79. doi: 10.3389/fonc.2013.00079.

From breast milk to brains: the potential of stem cells in human milk. Twigger AJ, Hodgetts S, Filgueira L, Hartmann PE, Hassiotou F. J Hum Lact. 2013 May;29(2):136-9. doi: 10.1177/0890334413475528. Epub 2013 Mar 20.

Pharmacological blocking of the osteoclastic biocorrosion of surgical stainless steel in vitro. Lionetto S, Little A, Moriceau G, Heymann D, Decurtins M, Plecko M, Filgueira L, Cadosch D. J Biomed Mater Res A. 2013 Apr;101(4):991-7. doi: 10.1002/jbm.a.34402.

Adipose tissue can be generated in vitro by using adipocytes from human fat tissue mesenchymal stem cells seeded and cultured on fibrin gel sheet. Tran CT, Huynh DT, Gargiulo C, Tran le BH, Huynh MH, Nguyen KH, Filgueira L, Strong DM. Cell Tissue Bank. 2013 Mar;14(1):97-106. doi: 10.1007/s10561-012-9304-6.

2012

Breastmilk is a novel source of stem cells with multilineage differentiation potential. Hassiotou F, Beltran A, Chetwynd E, Stuebe AM, Twigger AJ, Metzger P, Trengove N, Lai CT, Filgueira L, Blancafort P, Hartmann PE. Stem Cells. 2012 Oct;30(10):2164-74. doi: 10.1002/stem.1188.

A novel in vitro human microglia model: characterization of human monocyte-derived microglia. Etemad S, Zamin RM, Ruitenberg MJ, Filgueira L. J Neurosci Methods. 2012 Jul 30;209(1):79-89. doi: 10.1016/j.jneumeth.2012.05.025.

2011

Influence of metal ions on human lymphocytes and the generation of titanium-specific T-lymphocytes. Chan E, Cadosch D, Gautschi OP, Sprengel K, Filgueira L. J Appl Biomater Biomech. 2011 May-Aug;9(2):137-43. doi: 10.5301/JABB.2011.8567.

Visualising gold inside tumour cells following treatment with an antitumour gold(I) complex. Wedlock LE, Kilburn MR, Cliff JB, Filgueira L, Saunders M, Berners-Price SJ. Metallomics. 2011 Sep;3(9):917-25. doi: 10.1039/c1mt00053e.

Culture and differentiation of osteoblasts on coral scaffold from human bone marrow mesenchymal stem cells. Tran CT, Gargiulo C, Thao HD, Tuan HM, Filgueira L, Michael Strong D. Cell Tissue Bank. 2011 Nov;12(4):247-61. doi: 10.1007/s10561-010-9208-2. Epub 2010 Aug 12.

In vitro culture of Keratinocytes from human umbilical cord blood mesenchymal stem cells: the Saigonese culture. Tran CT, Huynh DT, Gargiulo C, Nguyen PT, Tran TT, Huynh MT, Nguyen TT, Filgueira L, Strong DM. Cell Tissue Bank. 2011 May;12(2):125-33. doi: 10.1007/s10561-010-9174-8.

2010

Biocorrosion and uptake of titanium by human osteoclasts. Cadosch D, Al-Mushaiqri MS, Gautschi OP, Meagher J, Simmen HP, Filgueira L. J Biomed Mater Res A. 2010 Dec 15;95(4):1004-10. doi: 10.1002/jbm.a.32914.

Titanium uptake, induction of RANK-L expression, and enhanced proliferation of human T-lymphocytes. Cadosch D, Sutanto M, Chan E, Mhawi A, Gautschi OP, von Katterfeld B, Simmen HP, Filgueira L. J Orthop Res. 2010 Mar;28(3):341-7. doi: 10.1002/jor.21013.

Metal ions: important co-players in aseptic loosening. Cadosch D, Schlett CL, Gautschi OP, Frei HC, Filgueira L. Z Orthop Unfall. 2010 Aug;148(4):393-7. doi: 10.1055/s-0030-1250108. Epub 2010 Aug 16. Review.

Functional and proteomic analysis of serum and cerebrospinal fluid derived from patients with traumatic brain injury: a pilot study. Cadosch D, Thyer M, Gautschi OP, Lochnit G, Frey SP, Zellweger R, Filgueira L, Skirving AP. ANZ J Surg. 2010 Jul-Aug;80(7-8):542-7. doi: 10.1111/j.1445-2197.2010.05268.x.

Serum after traumatic brain injury increases proliferation and supports expression of osteoblast markers in muscle cells. Cadosch D, Toffoli AM, Gautschi OP, Frey SP, Zellweger R, Skirving AP, Filgueira L. J Bone Joint Surg Am. 2010 Mar;92(3):645-53. doi: 10.2106/JBJS.I.00097.

Immune response deviation and enhanced expression of chemokine receptor CCR4 in TBI patients due to unknown serum factors. Cadosch D, Al-Mushaiqri MS, Gautschi OP, Chan E, Jung FJ, Skirving AP, Filgueira L. Injury. 2010 Jun;41(6):e4-9. doi: 10.1016/j.injury.2009.09.001.

Before 2010

Metal is not inert: role of metal ions released by biocorrosion in aseptic loosening--current concepts. Cadosch D, Chan E, Gautschi OP, Filgueira L. J Biomed Mater Res A. 2009 Dec 15;91(4):1252-62. doi: 10.1002/jbm.a.32625.

Effects of titanium(iv) ions on human monocyte-derived dendritic cells. Chan EP, Mhawi A, Clode P, Saunders M, Filgueira L. Metallomics. 2009 Mar;1(2):166-74. doi: 10.1039/b820871a.

Titanium induced production of chemokines CCL17/TARC and CCL22/MDC in human osteoclasts and osteoblasts. Cadosch D, Gautschi OP, Chan E, Simmen HP, Filgueira L. J Biomed Mater Res A. 2010 Feb;92(2):475-83. doi: 10.1002/jbm.a.32390.

Titanium IV ions induced human osteoclast differentiation and enhanced bone resorption in vitro.

Cadosch D, Chan E, Gautschi OP, Meagher J, Zellweger R, Filgueira L.

J Biomed Mater Res A. 2009 Oct;91(1):29-36. doi: 10.1002/jbm.a.32183.

Bio-corrosion of stainless steel by osteoclasts--in vitro evidence. Cadosch D, Chan E, Gautschi OP, Simmen HP, Filgueira L. J Orthop Res. 2009 Jul;27(7):841-6. doi: 10.1002/jor.20831.

Uptake and intracellular distribution of various metal ions in human monocyte-derived dendritic cells detected by Newport Green DCF diacetate ester. Cadosch D, Meagher J, Gautschi OP, Filgueira L. J Neurosci Methods. 2009 Mar 30;178(1):182-7. doi: 10.1016/j.jneumeth.2008.12.008.

CX3CL1/fractalkine regulates branching and migration of monocyte-derived cells in the mouse olfactory epithelium. Ruitenberg MJ, Vukovic J, Blomster L, Hall JM, Jung S, Filgueira L, McMenamin PG, Plant GW. J Neuroimmunol. 2008 Dec 15;205(1-2):80-5. doi: 10.1016/j.jneuroim.2008.09.010.

Functional dissociation of the basolateral transcytotic compartment from the apical phago-lysosomal compartment in human osteoclasts. Meagher J, Zellweger R, Filgueira L. J Histochem Cytochem. 2005 May;53(5):665-70.

Human dendritic cells process and present Listeria antigens for in vitro priming of autologous CD4+ T lymphocytes. Eppler E, Walch M, Latinovic-Golic S, Dumrese C, Filgueira L, Groscurth P. Histochem Cell Biol. 2005 Feb;123(2):169-78.

Rheumatoid arthritis synovium contains plasmacytoid dendritic cells. Cavanagh LL, Boyce A, Smith L, Padmanabha J, Filgueira L, Pietschmann P, Thomas R. Arthritis Res Ther. 2005;7(2):R230-40. 

Activation of dendritic cells by human papillomavirus-like particles through TLR4 and NF-kappaB-mediated signalling, moderated by TGF-beta. Yan M, Peng J, Jabbar IA, Liu X, Filgueira L, Frazer IH, Thomas R. Immunol Cell Biol. 2005 Feb;83(1):83-91.

Despite differences between dendritic cells and Langerhans cells in the mechanism of papillomavirus-like particle antigen uptake, both cells cross-prime T cells. Yan M, Peng J, Jabbar IA, Liu X, Filgueira L, Frazer IH, Thomas R. Virology. 2004 Jul 1;324(2):297-310.

Fluorescence-based staining for tartrate-resistant acidic phosphatase (TRAP) in osteoclasts combined with other fluorescent dyes and protocols. Filgueira L. J Histochem Cytochem. 2004 Mar;52(3):411-4.

Listeria species escape from the phagosomes of interleukin-4-deactivated human macrophages independent of listeriolysin. Neumann K, Eppler E, Filgueira L, Groscurth P, Gasal E, Schaffner A, Schoedon G, Schneemann M. Immunol Cell Biol. 2003 Dec;81(6):431-9.

Carcinoembryonic antigen (CEA) presentation and specific T cell-priming by human dendritic cells transfected with CEA-mRNA. Eppler E, Hörig H, Kaufman HL, Groscurth P, Filgueira L. Eur J Cancer. 2002 Jan;38(1):184-93.

Human skin Langerhans cells are targets of dengue virus infection. Wu SJ, Grouard-Vogel G, Sun W, Mascola JR, Brachtel E, Putvatana R, Louder MK, Filgueira L, Marovich MA, Wong HK, Blauvelt A, Murphy GS, Robb ML, Innes BL, Birx DL, Hayes CG, Frankel SS. Nat Med. 2000 Jul;6(7):816-20.

The lipid component of lipoproteins from Borrelia burgdorferi: structural analysis, antigenicity, and presentation via human dendritic cells. Beermann C, Lochnit G, Geyer R, Groscurth P, Filgueira L. Biochem Biophys Res Commun. 2000 Jan 27;267(3):897-905.

Potential strategies utilised by papillomavirus to evade host immunity. Frazer IH, Thomas R, Zhou J, Leggatt GR, Dunn L, McMillan N, Tindle RW, Filgueira L, Manders P, Barnard P, Sharkey M. Immunol Rev. 1999 Apr;168:131-42.

Human dermal dendritic cells process and present soluble protein antigens. Nestle FO, Filgueira L, Nickoloff BJ, Burg G. J Invest Dermatol. 1998 May;110(5):762-6.

The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand. Grouard G, Rissoan MC, Filgueira L, Durand I, Banchereau J, Liu YJ. J Exp Med. 1997 Mar 17;185(6):1101-11.

Dendritic cells capable of stimulating T cells in germinal centres. Grouard G, Durand I, Filgueira L, Banchereau J, Liu YJ. Nature. 1996 Nov 28;384(6607):364-7.

Human dendritic cells phagocytose and process Borrelia burgdorferi. Filgueira L, Nestlé FO, Rittig M, Joller HI, Groscurth P. J Immunol. 1996 Oct 1;157(7):2998-3005.

The pattern of cytokine gene expression in freshly excised human metastatic melanoma suggests a state of reversible anergy of tumor-infiltrating lymphocytes. Lüscher U, Filgueira L, Juretic A, Zuber M, Lüscher NJ, Heberer M, Spagnoli GC. Int J Cancer. 1994 May 15;57(4):612-9.

Binding and internalization of gold-labeled IFN-gamma by human Raji cells. Filgueira L, Groscurth P, Aguet M. J Immunol. 1989 May 15;142(10):3436-9.

Luis Filgueira - Anatomy - Department of Medicine - Rte Albert Gockel 1 - 1700 Freiburg - Tel +41 26 / 300 8441 - Fax +41 26 / 300 9733
luis.filgueira [at] unifr.ch - Swiss University